However, liraglutide achieved this primarily through a pronounced reduction in palatable food intake, whereas sibutramine reduced consumption of both chow and palatable foods (Hansen et al., 2012)
BMI does not measure body composition directly, and it may not accurately reflect the health or wellness of individuals of a specific race/ethnic group, those with high muscle mass, pregnant women, children, the elderly, or those with specific health conditions
This experiment was performed to examine the microglia-mediated inflammatory response in the brains of end-stage (14-week-old) untreated Pla2g6 / mice and the ability of high-dose semaglutide to prevent neuroinflammation
So while it is a known side effect, its still considered relatively uncommon
However, the proportion relative to total body mass increased by 3%